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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-5-13
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pubmed:abstractText |
Measuring local tissue temperature is critical in establishing a rational approach for hyperthermia treatment of tumors. We have found that the heme signals of myoglobin provide a unique basis for NMR thermometry in vivo. In particular the 5-methyl heme signal of MbCN exhibits a sharp, temperature-dependent resonance that is distinguishable in the tissue spectrum. Its calibrated chemical shift can then reflect the local tissue temperature in vivo.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
1226
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8155736-Animals,
pubmed-meshheading:8155736-Body Temperature,
pubmed-meshheading:8155736-Hyperthermia, Induced,
pubmed-meshheading:8155736-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8155736-Muscles,
pubmed-meshheading:8155736-Myoglobin,
pubmed-meshheading:8155736-Neoplasms,
pubmed-meshheading:8155736-Rats,
pubmed-meshheading:8155736-Rats, Sprague-Dawley
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pubmed:year |
1994
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pubmed:articleTitle |
Myoglobin signal as an NMR tissue thermometer: implication for hyperthermia treatment of tumors.
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pubmed:affiliation |
Department of Biological Chemistry, University of California Davis 95616-8635.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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