Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1994-4-29
|
| pubmed:abstractText |
The records of 100 lung transplant recipients (13 heart-lungs, 45 double-lungs, and 42 single-lungs) from September 1990 through April 1992 were reviewed to determine the role of cardiopulmonary bypass (CPB) in early graft dysfunction. Fifty-five patients requiring CPB (CPB group) for 186 +/- 54 minutes were compared with the 45 patients without CPB (no-CPB group). All of the heart-lung and en-bloc double-lung transplantations were performed under CPB, with pulmonary vascular lung disease the principal diagnosis, resulting in a significantly younger age population in the CPB group. All other donor- and recipient-related factors matched well in both groups. Of 38 bilateral single-lung transplantations, CPB was used in 18. In double-lung and heart-lung recipients gas exchange of the allografts was evaluated by the arterial/alveolar oxygen tension ratios at nine intervals during the first 72 hours. The mean arterial/alveolar oxygen tension ratio in the CPB group was 0.48 +/- 0.19, significantly lower than in the no-CPB group with 0.60 +/- 0.22 (p = 0.025). All patients had radiographic interpretation and scoring of pulmonary infiltrates from chest roentgenograms taken within 12 hours after reperfusion. The CPB group had more severe pulmonary infiltrates than the no-CPB group (p = 0.034). Prolonged intubation defined as 7 days or longer occurred significantly more often (29/55) in the CPB group than in the no-CPB group (8/45) (p = 0.003). Actuarial graft and patient survival at 1 month was better in the no-CPB group than in the CPB group (42/45 versus 44/55 [p = 0.05] and 43/45 versus 45/55 [p = 0.033], respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0003-4975
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
57
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
715-22
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8147645-Adolescent,
pubmed-meshheading:8147645-Adult,
pubmed-meshheading:8147645-Biopsy,
pubmed-meshheading:8147645-Cardiopulmonary Bypass,
pubmed-meshheading:8147645-Child,
pubmed-meshheading:8147645-Female,
pubmed-meshheading:8147645-Graft Survival,
pubmed-meshheading:8147645-Heart-Lung Transplantation,
pubmed-meshheading:8147645-Humans,
pubmed-meshheading:8147645-Intubation, Intratracheal,
pubmed-meshheading:8147645-Lung,
pubmed-meshheading:8147645-Lung Transplantation,
pubmed-meshheading:8147645-Male,
pubmed-meshheading:8147645-Middle Aged,
pubmed-meshheading:8147645-Oxygen,
pubmed-meshheading:8147645-Pulmonary Alveoli,
pubmed-meshheading:8147645-Pulmonary Gas Exchange,
pubmed-meshheading:8147645-Radiography, Thoracic,
pubmed-meshheading:8147645-Survival Rate
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Effect of cardiopulmonary bypass on early graft dysfunction in clinical lung transplantation.
|
| pubmed:affiliation |
Division of Cardiothoracic Surgery, University of Pittsburgh, Pennsylvania.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|