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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1994-3-29
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pubmed:databankReference |
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pubmed:abstractText |
A cDNA for a serine/threonine kinase receptor was isolated from a mouse brain cDNA library. The receptor transiently expressed on COS cells bound TGF-beta 1 not by itself but only when TGF-beta type II receptor was coexpressed. The molecular mass of the ligand-receptor complex was estimated to be 75 kDa. The type II receptor-dependent binding and the molecular mass of the complex suggest that the receptor is a TGF-beta type I receptor.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-291X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
198
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1063-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8117262-Amino Acid Sequence,
pubmed-meshheading:8117262-Animals,
pubmed-meshheading:8117262-Base Sequence,
pubmed-meshheading:8117262-Blotting, Northern,
pubmed-meshheading:8117262-Brain,
pubmed-meshheading:8117262-Cell Line,
pubmed-meshheading:8117262-DNA, Complementary,
pubmed-meshheading:8117262-DNA Primers,
pubmed-meshheading:8117262-Gene Expression,
pubmed-meshheading:8117262-Gene Library,
pubmed-meshheading:8117262-Mice,
pubmed-meshheading:8117262-Molecular Sequence Data,
pubmed-meshheading:8117262-Organ Specificity,
pubmed-meshheading:8117262-Protein-Serine-Threonine Kinases,
pubmed-meshheading:8117262-Receptors, Transforming Growth Factor beta,
pubmed-meshheading:8117262-Recombinant Proteins,
pubmed-meshheading:8117262-Sequence Homology, Amino Acid,
pubmed-meshheading:8117262-Transfection
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pubmed:year |
1994
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pubmed:articleTitle |
A mouse TGF-beta type I receptor that requires type II receptor for ligand binding.
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pubmed:affiliation |
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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