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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1994-3-22
|
| pubmed:abstractText |
A nonglycosylated (N30QN78Q) form of the human tissue inhibitor of metalloproteinases, TIMP-1, has been prepared and crystallized in a form suitable for X-ray diffraction analysis. Small single crystals have been grown using sodium tartrate as a precipitant. The crystals are in space group P2(1), with cell dimensions a = 35.28, b = 53.95, c = 48.56, and beta = 96.0 degrees. There is a single molecule of TIMP-1 in the asymmetric unit. The crystals diffract to at least 2.3 A resolution. Complete data have been collected to 2.9 A and a search for heavy-metal derivatives is in progress.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0887-3585
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
435-7
|
| pubmed:dateRevised |
2010-8-25
|
| pubmed:meshHeading |
pubmed-meshheading:8108384-Base Sequence,
pubmed-meshheading:8108384-Crystallography,
pubmed-meshheading:8108384-Glycoproteins,
pubmed-meshheading:8108384-Glycosylation,
pubmed-meshheading:8108384-Metalloendopeptidases,
pubmed-meshheading:8108384-Molecular Sequence Data,
pubmed-meshheading:8108384-Mutagenesis, Site-Directed,
pubmed-meshheading:8108384-Tissue Inhibitor of Metalloproteinases,
pubmed-meshheading:8108384-X-Ray Diffraction
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Crystallization and preliminary X-ray analysis of nonglycosylated tissue inhibitor of metalloproteinases-1, N30QN78Q TIMP-1.
|
| pubmed:affiliation |
Department of Chemistry, University of York, Heslington, England.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|