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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-8-27
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pubmed:abstractText |
The expression of intercellular adhesion molecule-1 (ICAM-1) was investigated in frozen sections obtained from 40 resected liver specimens of patients with hepatocellular carcinoma using immunoperoxidase techniques and immunoelectron microscopy. ICAM-1 was expressed in 80% of the HCC specimens on the membrane of cancer cells. In noncancerous regions characterized by cirrhosis in 28 cases and chronic hepatitis in 12 cases, ICAM-1 was rarely expressed on hepatocytes but was expressed mainly on the endothelium of portal vessels and sinusoidal lining cells. These results suggest that expression of ICAM-1 in hepatocellular carcinoma may be induced by malignant transformation of hepatocytes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-4790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8101890-Aged,
pubmed-meshheading:8101890-Carcinoma, Hepatocellular,
pubmed-meshheading:8101890-Cell Adhesion Molecules,
pubmed-meshheading:8101890-Chi-Square Distribution,
pubmed-meshheading:8101890-Female,
pubmed-meshheading:8101890-Frozen Sections,
pubmed-meshheading:8101890-Humans,
pubmed-meshheading:8101890-Immunoenzyme Techniques,
pubmed-meshheading:8101890-Intercellular Adhesion Molecule-1,
pubmed-meshheading:8101890-Liver Neoplasms,
pubmed-meshheading:8101890-Male,
pubmed-meshheading:8101890-Microscopy, Immunoelectron,
pubmed-meshheading:8101890-Middle Aged
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pubmed:year |
1993
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pubmed:articleTitle |
Expression of intercellular adhesion molecule-1 in hepatocellular carcinoma.
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pubmed:affiliation |
Department of Surgery II, Nagoya University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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