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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1994-8-30
|
| pubmed:abstractText |
Gastrocnemius muscle from treadmill trained rats was analyzed for creatine kinase (CK) isoenzyme activities by agarose electrophoresis and M and B CK mRNA levels by Northern blot analysis. Total CK activity in exercise-trained (143 (SD 15) U/g) and control (154 (SD 16) U/g) muscles did not differ. CK-MB increased 220% in exercised-trained muscle compared to controls. CK-B subunit mRNA increased 40%, while CK-M subunit mRNA decreased 42% in exercised-trained muscle compared to control. Thus, gene expression of CK isoenzymes appears to be partially controlled at the level of transcription following exercise training.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0024-3205
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
585-92
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:8046994-Animals,
pubmed-meshheading:8046994-Creatine Kinase,
pubmed-meshheading:8046994-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:8046994-Isoenzymes,
pubmed-meshheading:8046994-Muscles,
pubmed-meshheading:8046994-Physical Exertion,
pubmed-meshheading:8046994-RNA, Messenger,
pubmed-meshheading:8046994-Rats,
pubmed-meshheading:8046994-Rats, Sprague-Dawley
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Expression of creatine kinase M and B mRNAs in treadmill trained rat skeletal muscle.
|
| pubmed:affiliation |
Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, University of Minnesota School of Medicine, Minneapolis 55415.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|