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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1994-12-30
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pubmed:databankReference |
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pubmed:abstractText |
The first allele of string of pearls (sop) was isolated as a recessive female sterile mutant in a P element enhancer trap screen. Oogenesis in homozygous sop females arrests at approximately stage 5. In addition, homozygous flies of both sexes have Minute-like characteristics that include reduced bristles, delayed development and larval lethality. sop maps to 30D/E on chromosome 2L and encodes the Drosophila homolog of eukaryotic ribosomal protein S2. The gene is present in a single copy in the Drosophila genome and the level of mRNA present in mutant animals is reduced. The identification of a mutant allele that blocks development at a mid-stage of oogenesis may indicate that sop has a specific developmental role during oogenesis in addition to its general role in protein synthesis as a component of the small ribosomal subunit.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1105158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1291154,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1339308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1454811,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1541393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-17246182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-17246581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-17246916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-17247676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1745245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-1939063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2279698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2308862,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2492966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2499514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2503422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2503424,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2505058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2827169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2835286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2877746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-2882603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3000622,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3082713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3140040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3162770,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3185506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3370670,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3936537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-3939320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-4047173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-405273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-406151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-408229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-4624779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-4631602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-6432334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-6771656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-6795082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-814037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-8269846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-8441641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-8453663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7982558-8514131
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-6731
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
137
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pubmed:geneSymbol |
sop
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1039-48
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:7982558-Alleles,
pubmed-meshheading:7982558-Amino Acid Sequence,
pubmed-meshheading:7982558-Animals,
pubmed-meshheading:7982558-Base Sequence,
pubmed-meshheading:7982558-Drosophila melanogaster,
pubmed-meshheading:7982558-Female,
pubmed-meshheading:7982558-Genes, Insect,
pubmed-meshheading:7982558-Genes, Recessive,
pubmed-meshheading:7982558-Infertility, Female,
pubmed-meshheading:7982558-Male,
pubmed-meshheading:7982558-Molecular Sequence Data,
pubmed-meshheading:7982558-Oogenesis,
pubmed-meshheading:7982558-Phenotype,
pubmed-meshheading:7982558-Ribosomal Proteins,
pubmed-meshheading:7982558-Sequence Alignment,
pubmed-meshheading:7982558-Sequence Homology, Amino Acid,
pubmed-meshheading:7982558-Species Specificity
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pubmed:year |
1994
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pubmed:articleTitle |
string of pearls encodes Drosophila ribosomal protein S2, has Minute-like characteristics, and is required during oogenesis.
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pubmed:affiliation |
Department of Biology, University of California, Los Angeles 90024.
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pubmed:publicationType |
Journal Article
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