|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0017526,
umls-concept:C0021745,
umls-concept:C0063695,
umls-concept:C0079411,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C1522492,
umls-concept:C1704711,
umls-concept:C2247825,
umls-concept:C2911684
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1994-12-27
|
|
pubmed:abstractText |
Multinucleated giant cells (MGC), interferon-gamma (IFN-gamma) production, and increased expression of adhesion molecules are features of granulomatous reactions. IFN-gamma induces the fusion of macrophages and the subsequent MGC generation in vitro. Moreover, IFN-gamma increases ICAM-1 expression on lymphoid cells and an important role for adhesion molecules in MGC generation has been proposed.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0023-6837
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
71
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
737-44
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1994
|
|
pubmed:articleTitle |
Multinucleated giant cells generation induced by interferon-gamma. Changes in the expression and distribution of the intercellular adhesion molecule-1 during macrophages fusion and multinucleated giant cell formation.
|
|
pubmed:affiliation |
Istituti di Clinica Medica 2, Virologia, di Anatomia Patologica 2 Universita' La Sapienza, Roma, Italy.
|
|
pubmed:publicationType |
Journal Article,
In Vitro
|
