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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-4-27
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pubmed:abstractText |
We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The investigations were repeated after 11-20 months (mean 15.6). The macro MUP amplitudes in both patient groups were markedly increased (P = 0.02). However, no statistical difference was found between the two groups in the initial amplitude values. Macro MUP amplitudes obtained on repeated examinations did not differ significantly from the initial macro MUP amplitudes in any of the three groups. In three individual PPS patients, a decline in muscle strength on the follow-up study was documented, providing the diagnosis of post-poliomyelitis muscular atrophy (PPMA). The three PPMA patients had the highest initial macro MUPs. Two of them showed a decrease in macro MUP amplitudes on follow-up. These findings suggest that a later breakdown of oversized MUs may play a role in the pathogenesis of PPMA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0340-5354
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
242
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-40
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7897450-Adult,
pubmed-meshheading:7897450-Electromyography,
pubmed-meshheading:7897450-Female,
pubmed-meshheading:7897450-Follow-Up Studies,
pubmed-meshheading:7897450-Humans,
pubmed-meshheading:7897450-Male,
pubmed-meshheading:7897450-Middle Aged,
pubmed-meshheading:7897450-Muscle, Skeletal,
pubmed-meshheading:7897450-Muscular Atrophy,
pubmed-meshheading:7897450-Neural Conduction,
pubmed-meshheading:7897450-Postpoliomyelitis Syndrome,
pubmed-meshheading:7897450-Prospective Studies
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pubmed:year |
1994
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pubmed:articleTitle |
Macro EMG follow-up study in post-poliomyelitis patients.
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pubmed:affiliation |
Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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