Linked Life Data

7835989

Source:http://linkedlifedata.com/resource/pubmed/id/7835989

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1995-3-2
pubmed:abstractText
Lymphocyte subpopulations in cord blood (CB; collected at birth from full-term babies) were compared with that of adult blood (AB) and found to contain significantly different numbers and percentages of lymphocyte subpopulations. The absolute lymphocyte count was greater in CB (4.8 +/- 1.1 x 10(9)/L) than in AB (1.69 +/- 0.38 x 10(9)/L), with CB having significantly higher absolute numbers of lymphocyte subsets even though CB percentages were significantly lower. Significant differences in percentages were found between cord and adult T cells (CB 58% vs AB 74%), NK cells (CB 19% vs AB 7%) and their subsets. CD38, a marker of activation and immaturity, was present on virtually all cord T cells and approximately half the adult T cells. CD45RA, a marker considered to define unprimed or naive cells, was expressed on 82% of cord lymphocytes as compared with 48% in AB. CD45RO was expressed on 16% of CB lymphocytes and 49% of AB lymphocytes. Cord blood contains a higher percentage and total number of immature and immunologically naive lymphocytes than AB.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0818-9641
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
440-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Comparison of cord blood and adult blood lymphocyte normal ranges: a possible explanation for decreased severity of graft versus host disease after cord blood transplantation.
pubmed:affiliation
Bone Marrow Transplant Laboratory, Prince of Wales Children's Hospital, Randwick, New South Wales, Australia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't