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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1995-7-10
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pubmed:abstractText |
A case of enteropathy associated T-cell lymphoma (EATCL) in a 62-year-old female with a previous history of coeliac disease, complicated during the clinical course by massive blood and tissue eosinophilia is described. The patient's serum contained a factor capable of stimulating the in vitro growth of eosinophilic colonies (CFU-Eo), that was absent in the serum of normal donors. We suggest that such factor was Interleukin-5 (IL-5), as indicated by the presence in the monoclonal tumor T cells of IL-5 encoding mRNA, usually absent in the normal enterocytes of the jejunum.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1042-8194
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
155-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7773153-Cell Division,
pubmed-meshheading:7773153-DNA, Neoplasm,
pubmed-meshheading:7773153-Eosinophilia,
pubmed-meshheading:7773153-Female,
pubmed-meshheading:7773153-Flow Cytometry,
pubmed-meshheading:7773153-Hematopoietic Stem Cells,
pubmed-meshheading:7773153-Humans,
pubmed-meshheading:7773153-Immunohistochemistry,
pubmed-meshheading:7773153-Immunophenotyping,
pubmed-meshheading:7773153-Interleukin-5,
pubmed-meshheading:7773153-Intestinal Neoplasms,
pubmed-meshheading:7773153-Lymphoma, T-Cell,
pubmed-meshheading:7773153-Middle Aged,
pubmed-meshheading:7773153-RNA, Messenger
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pubmed:year |
1995
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pubmed:articleTitle |
Intestinal T-cell lymphoma with massive tissue and blood eosinophilia mediated by IL-5.
|
pubmed:affiliation |
Divisione di Medicina, University of Torino, Italy.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|