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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-5-25
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pubmed:abstractText |
The effects of pristane on some immunity parameters in BALB/c mice were studied. The intraperitoneal administration of a single dose of pristane induced a strong inflammatory reaction that lasted longer than 10 days. When mice were immunized with sheep erythrocytes 10 days after pristane administration, the response of hemolytic IgM-forming cells was increased and that of hemolytic IgG-forming cells was decreased; however, the total number of antibody-forming cells did not change. The proliferative response of splenocytes to concanavalin A was increased in mice that received pristane 10 days earlier. Development of the syngeneic NS1 plasmacytoma was enhanced by administration of pristane 2 days or 10 days before tumor transplantation. We concluded that enhancement of plasmacytoma development was not due to immunosuppressive properties of pristane but to other factors such as ascites induction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0165-2478
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7721342-Animals,
pubmed-meshheading:7721342-Antibody-Producing Cells,
pubmed-meshheading:7721342-Immunosuppressive Agents,
pubmed-meshheading:7721342-Lymphocyte Activation,
pubmed-meshheading:7721342-Male,
pubmed-meshheading:7721342-Mice,
pubmed-meshheading:7721342-Mice, Inbred BALB C,
pubmed-meshheading:7721342-Mitogens,
pubmed-meshheading:7721342-Neoplasm Transplantation,
pubmed-meshheading:7721342-Peritoneal Cavity,
pubmed-meshheading:7721342-Plasmacytoma,
pubmed-meshheading:7721342-Sheep,
pubmed-meshheading:7721342-Spleen,
pubmed-meshheading:7721342-Terpenes
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pubmed:year |
1995
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pubmed:articleTitle |
The enhancement of growth of a syngeneic plasmacytoma in BALB/c mice by pristane priming is not due to immunosuppressive effects on antibody-forming cell or mitogen-responsive splenocytes.
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pubmed:affiliation |
Departamento de Microbiología, Facultad de Farmacia, Universidad de Granada, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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