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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1995-9-13
|
| pubmed:abstractText |
Interaction of the CD11/CD18 complex on polymorphonuclear neutrophils (PMNs) and intercellular adhesion molecule (ICAM)-1 on endothelium is a critical event in PMN-mediated tissue injury. In addition, increased expression of ICAM-1 on type I pneumocytes has been identified in a variety of pulmonary disorders associated with PMN-induced inflammation. We hypothesized that ICAM-1 up-regulation is sufficient to promote cytotoxicity via activated PMNs.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0039-6060
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
118
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
171-5; discussion 176
|
| pubmed:dateRevised |
2010-3-24
|
| pubmed:meshHeading |
pubmed-meshheading:7638730-Animals,
pubmed-meshheading:7638730-CHO Cells,
pubmed-meshheading:7638730-Cricetinae,
pubmed-meshheading:7638730-Cytotoxicity, Immunologic,
pubmed-meshheading:7638730-Humans,
pubmed-meshheading:7638730-Intercellular Adhesion Molecule-1,
pubmed-meshheading:7638730-Neutrophils,
pubmed-meshheading:7638730-Transfection
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Intercellular adhesion molecule-1 promotes neutrophil-mediated cytotoxicity.
|
| pubmed:affiliation |
Department of Surgery, Denver General Hospital, Colo 80204, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|