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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-9-5
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pubmed:abstractText |
The authors determined the desoxyribonucleic acid (DNA) content of 45 small-cell lung cancers, by flow-cytometry (FC), from bronchial brushings to asses the prognostic meaning of the DNA index, the percentage of cells in DNA synthesis phase (% S) and the ploidy. Moreover, the value of this tumorous cells brushing was assessed for Flow-cytometric analysis. Bronchial brushing offers some advantages opposite to biopsies, but the low quantity of collected cells reduces the number of tumors analysable by FC. The output is low (39%) for determination of DNA index, and moreover low (22%) for determination of % S. In regard to the flow-cytometry analysis, the DNA content does not show any significant difference of survival where as the % S is related to survival, but it seems to be paradoxical in this study. Indeed, patients with small-cell lung cancer associated to high cells' percentage in DNA synthesis phase have the longest survival.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0007-4551
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
364-70
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7626844-Bronchi,
pubmed-meshheading:7626844-Bronchoscopy,
pubmed-meshheading:7626844-Carcinoma, Small Cell,
pubmed-meshheading:7626844-DNA, Neoplasm,
pubmed-meshheading:7626844-Evaluation Studies as Topic,
pubmed-meshheading:7626844-Female,
pubmed-meshheading:7626844-Fiber Optic Technology,
pubmed-meshheading:7626844-Flow Cytometry,
pubmed-meshheading:7626844-Humans,
pubmed-meshheading:7626844-Lung Neoplasms,
pubmed-meshheading:7626844-Male,
pubmed-meshheading:7626844-Neoplasm Staging,
pubmed-meshheading:7626844-Prognosis,
pubmed-meshheading:7626844-Retrospective Studies,
pubmed-meshheading:7626844-Survival Rate
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pubmed:year |
1995
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pubmed:articleTitle |
[Prognostic evaluation of small cell lung carcinoma by flow cytometry. A retrospective study from bronchial brushing samples].
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pubmed:affiliation |
Service de pneumologie, CHU, Angers, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|