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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-8-15
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pubmed:abstractText |
Chronic pyelonephritis was successfully produced in female BALB/c mice with Escherichia coli after introduction of the bacterial inoculum by the ascending route. E. coli strain 31-B, a nalidixic acid-resistant derivative of strain TN675 expressing type-1 pili, and E. coli strain BH-5, a mutant of 31-B, not expressing type-1 pili, were used in the model. Both the strains were able to induce chronic renal inflammation in the experimental animals. Whereas the initial colonisation was greater with strain 31-B, its non-pilate mutant BH-5 caused a significantly greater inflammatory response and also caused renal scarring observable 5 months after the infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-2615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7608952-Animals,
pubmed-meshheading:7608952-Chronic Disease,
pubmed-meshheading:7608952-Disease Models, Animal,
pubmed-meshheading:7608952-Escherichia coli,
pubmed-meshheading:7608952-Escherichia coli Infections,
pubmed-meshheading:7608952-Female,
pubmed-meshheading:7608952-Fimbriae, Bacterial,
pubmed-meshheading:7608952-Kidney,
pubmed-meshheading:7608952-Mice,
pubmed-meshheading:7608952-Mice, Inbred BALB C,
pubmed-meshheading:7608952-Pyelonephritis
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pubmed:year |
1995
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pubmed:articleTitle |
An ascending non-obstructive model for chronic pyelonephritis in BALB/c mice.
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pubmed:affiliation |
Department of Microbiology, Government Medical College, Chandigarh, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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