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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-8-16
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pubmed:abstractText |
Ninety-nine classical and 11 atypical bronchopulmonary carcinoids were investigated immunohistochemically with an antibody against secretoneurin, a peptide proteolytically processed from secretogranin II (chromogranin C), as well as antibodies against chromogranin A and B and secretogranin II. Secretoneurin was immunolocalized in 86 tumours (78 classical and eight atypical carcinoids); secretogranin II was found in the same tumours in a similar distribution, whereas chromogranin A was present in all 100 and chromogranin B in 106 tumours investigated. Bronchopulmonary carcinoids are usually not associated with clinically or biochemically distinct syndromes. Although we found bronchial carcinoids with different immunohistochemical chromogranins/secretogranin patterns, no correlation with the biological behaviour of these tumours could be demonstrated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chromogranin A,
http://linkedlifedata.com/resource/pubmed/chemical/Chromogranins,
http://linkedlifedata.com/resource/pubmed/chemical/Neuropeptides,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Secretogranin II,
http://linkedlifedata.com/resource/pubmed/chemical/secretoneurin
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0309-0167
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7607625-Carcinoid Tumor,
pubmed-meshheading:7607625-Chromogranin A,
pubmed-meshheading:7607625-Chromogranins,
pubmed-meshheading:7607625-Humans,
pubmed-meshheading:7607625-Immunohistochemistry,
pubmed-meshheading:7607625-Lung Neoplasms,
pubmed-meshheading:7607625-Neuropeptides,
pubmed-meshheading:7607625-Proteins,
pubmed-meshheading:7607625-Secretogranin II
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pubmed:year |
1995
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pubmed:articleTitle |
Secretoneurin in bronchopulmonary carcinoids--immunohistochemical comparison with chromogranins A and B and secretogranin II.
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pubmed:affiliation |
Department of Pathology, University of Münster, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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