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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1995-8-7
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pubmed:abstractText |
The proposal that Kaposi's sarcoma undergoes cellular transformation from early to late stages was studied with argyrophilic nucleolar organizer regions, proliferating cell nuclear antigen/cyclin, and immunoperoxidase staining for factor VIII-related antigen. Staining of argyrophilic nucleolar organizer regions was significantly increased in the plaque/nodular stage compared to the patch stage. The endothelial-selective marker factor VIII-related antigen stained more intensely in patch stage lesions. This was inversely correlated with staining of argyrophilic nucleolar organizer regions. Proliferating cell nuclear antigen/cyclin staining did not correlate with tumor stage or with factor VIII-related antigen. The changes in argyrophilic nucleolar organizer regions and factor VIII-related antigen staining are evidence for cellular transformation in Kaposi's sarcoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0003-9985
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
538-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7605171-Humans,
pubmed-meshheading:7605171-Immunoenzyme Techniques,
pubmed-meshheading:7605171-Nucleolus Organizer Region,
pubmed-meshheading:7605171-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:7605171-Sarcoma, Kaposi,
pubmed-meshheading:7605171-Silver Staining,
pubmed-meshheading:7605171-von Willebrand Factor
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pubmed:year |
1995
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pubmed:articleTitle |
Argyrophilic nucleolar organizer regions and proliferating cell nuclear antigen/cyclin in Kaposi's sarcoma. Comparison with morphology and with immunoperoxidase staining for factor VIII-related antigen.
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pubmed:affiliation |
Department of Pathology, Pennsylvania Hospital, Philadelphia 19107, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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