Linked Life Data

7526951

Source:http://linkedlifedata.com/resource/pubmed/id/7526951

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-1-4
pubmed:abstractText
Paranode-node-paranode regions of the nerve fibre interact in a fundamental manner with the transport of axoplasmic material. The aim of the study was to examine the ultrastructure of Ranvier's node in sciatic nerve of rabbits treated with vincristine. The results showed accumulation of organelles in Ranvier's nodes of affected animals. Organelles arrested in this region disturbed each other and degenerated. Some of them were sequestered from the axon by Schwann cell fingers and terminal loops, but often this process was not sufficient to prevent nerve fibre against degeneration. In conclusion our results provided evidence that Ranvier's node become locus minoris resistentiae in vincristine affected nerve fibers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1641-4640
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Ultrastructure of the Ranvier's node in vincristine neuropathy.
pubmed:affiliation
Laboratory of Developmental Neuropathology, Medical Research Centre, Polish Academy of Sciences, Warszawa.
pubmed:publicationType
Journal Article, Comparative Study