Linked Life Data

7518648

Source:http://linkedlifedata.com/resource/pubmed/id/7518648

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-8-12
pubmed:abstractText
This study compared conventional light microscopy with immunohistochemistry in the histopathologic diagnosis of intrauterine pregnancy in curettings in which fetal parts and chorionic villi were absent. Hematoxylin and eosin-stained sections of the curettings, which were from 50 consecutive patients in whom incomplete abortion had been diagnosed clinically, were circulated to four pathologists who graded their diagnoses with a confidence score. Immunohistochemical examination using a standard streptavidin-biotin-peroxidase method with anti-HPL and antikeratin antisera was performed. The pathologists in the maternity hospitals achieved a high level of diagnostic confidence compared with those working in the general hospitals. However, there were erroneous diagnoses by the one pathologist in the former group and none by the latter. Critical path analysis showed that the best performing pathologist could accurately diagnose all but two of the cases that had been diagnosed with a degree of doubt by the other pathologists without recourse to immunohistochemical examination. These results suggest that immunohistochemistry may be used discriminately in uncertain cases or if relatively inexperienced pathologists are reporting.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
72-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The usefulness of human placental lactogen and keratin immunohistochemistry in the assessment of tissue from purported intrauterine pregnancies.
pubmed:affiliation
Department of Pathology, Queen Victoria Hospital, Australia.
pubmed:publicationType
Journal Article