Linked Life Data

7511941

Source:http://linkedlifedata.com/resource/pubmed/id/7511941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1994-5-6
pubmed:abstractText
Granulocyte colony-stimulating factor (G-CSF) regulates the production and potentiates the function of neutrophils. Studies of animals and patients have shown that levels of G-CSF increase in response to certain types of acute bacterial infection; for example, levels of this factor increase in the lungs and in serum during pneumonia. Investigations of several nonneutropenic animal models of severe bacterial infection have indicated that exogenous recombinant G-CSF--either alone or in combination with antibiotics--can significantly enhance host defenses and improve rates of survival. Trials of recombinant G-CSF for the prevention or treatment of serious infection in clinical settings have recently been initiated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1058-4838
pubmed:author
pubmed:issnType
Print
pubmed:volume
18 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S197-204
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Role of granulocyte colony-stimulating factor in the immune response to acute bacterial infection in the nonneutropenic host: an overview.
pubmed:affiliation
Section of Pulmonary/Critical Care Medicine, Louisiana State University Medical Center, New Orleans.
pubmed:publicationType
Journal Article, Review