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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0001644,
umls-concept:C0006784,
umls-concept:C0028606,
umls-concept:C0034493,
umls-concept:C0040300,
umls-concept:C0043100,
umls-concept:C0054534,
umls-concept:C0204695,
umls-concept:C0427716,
umls-concept:C0441655,
umls-concept:C0442043,
umls-concept:C0871261,
umls-concept:C1304757,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
1994-4-28
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pubmed:abstractText |
Forty-eight crossbred rabbits were used in three replications of a 2 x 4 factorial arrangement to investigate the short-term responses of tissue accretion, calpains and calpastatin activity, and nucleic acid and protein concentrations to beta-adrenergic agonist (BAA) feeding. Rabbits were fed a 17% CP diet with or without 7 ppm of L644,969 and slaughtered after 1, 4, 8, or 16 d of treatment. Empty body dressing percentage and biceps femoris weight (as a percentage of empty body weight [EBW]) were significantly higher in the treated rabbits than in the controls after 16 d of treatment. Heart and liver weights (as a percentage of EBW) were higher (P < .05) after 1 d and liver weight (as a percentage of EBW) was lower (P < .05) after 16 d in treated vs controls. Except for an elevation of skeletal muscle m-calpain after 16 d, BAA-supplementation did not affect the calpain-calpastatin system. Muscle RNA concentrations and RNA:DNA ratios were higher (P < .05) in treated rabbits after 1 d and remained higher thereafter. Protein:RNA ratios were lower (P < .01) in treated than in control rabbits after 4 d and remained lower throughout the trial. Muscle DNA content was lower after 4 d and higher after 16 d; RNA content was higher after 4, 8, and 16 d; and protein content was higher after 16 d in treated vs control rabbits. Liver nucleic acid and protein concentrations were not affected by BAA treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/6-amino-alpha-(((1-methyl-3-phenylpr...,
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Calpain,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Muscle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/calpastatin
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-8812
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-74
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:7511137-Adrenergic beta-Agonists,
pubmed-meshheading:7511137-Animals,
pubmed-meshheading:7511137-Blood Urea Nitrogen,
pubmed-meshheading:7511137-Calcium-Binding Proteins,
pubmed-meshheading:7511137-Calpain,
pubmed-meshheading:7511137-DNA,
pubmed-meshheading:7511137-Female,
pubmed-meshheading:7511137-Heart,
pubmed-meshheading:7511137-Liver,
pubmed-meshheading:7511137-Muscle Development,
pubmed-meshheading:7511137-Muscle Proteins,
pubmed-meshheading:7511137-Muscles,
pubmed-meshheading:7511137-Myocardium,
pubmed-meshheading:7511137-Organ Size,
pubmed-meshheading:7511137-Pyridines,
pubmed-meshheading:7511137-RNA,
pubmed-meshheading:7511137-Rabbits
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pubmed:year |
1994
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pubmed:articleTitle |
Temporal response of rabbits to beta-adrenergic agonist feeding: tissue weight, calpains and calpastatin activities, and nucleic acid and protein concentrations.
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pubmed:affiliation |
Department of Animal Science, University of Nebraska, Lincoln 68583-0908.
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pubmed:publicationType |
Journal Article
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