Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-2-26
pubmed:abstractText
Temperature-sensitive mutants of Alcaligenes faecalis that exhibited reduced growth at 42 C but grew well at 30 C were induced by N-methyl-N'-nitro-N-nitrosoguanidine. Four of the 5 mutants that were studied readily colonized the nasal mucosa of turkeys when given intranasally or in drinking water. Several mutants caused no signs of coryza or depression and produced minimal colonization of the trachea. Colonization of the nasal mucosa lasted 3 to 4 weeks and induced moderate levels of serum antibodies. When challenged with virulent isolates of A. faecalis 4 to 6 weeks after having been exposed to the mutants, unstressed turkeys were protected; turkeys subjected to water deprivation exhibited some colonization with the virulent strain and showed slight signs of coryza.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0005-2086
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
726-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Immunization against turkey coryza by colonization with mutants of Alcaligenes faecalis.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't