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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1981-2-24
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pubmed:abstractText |
Sister chromatid exchanges and chromosomal aberrations were investigated in lymphocytes from 11 children with malignant lymphoma after cessation of treatment. Chemotherapy combined with radiation was administered, terminating between 4 months and 13 years before chromosome analyses were performed. The frequency of sister chromatid exchanges per chromosome was the same, 0.20, in the patients and a matched control group, although there was a significant heterogeneity between individuals. The number of cells with chromosome abnormalities increased from 2.9% in control children to 4.8% in treated patients, a nonsignificant increase. Only translocations showed a significant increase.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
4786-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7438111-Adolescent,
pubmed-meshheading:7438111-Antineoplastic Agents,
pubmed-meshheading:7438111-Child,
pubmed-meshheading:7438111-Child, Preschool,
pubmed-meshheading:7438111-Chromosome Aberrations,
pubmed-meshheading:7438111-Crossing Over, Genetic,
pubmed-meshheading:7438111-Drug Therapy, Combination,
pubmed-meshheading:7438111-Female,
pubmed-meshheading:7438111-Humans,
pubmed-meshheading:7438111-Lymphoma,
pubmed-meshheading:7438111-Male,
pubmed-meshheading:7438111-Radiotherapy,
pubmed-meshheading:7438111-Sister Chromatid Exchange
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pubmed:year |
1980
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pubmed:articleTitle |
Sister chromatid exchanges and chromosome aberrations in children after treatment for malignant lymphoma.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|