Linked Life Data

7422007

Source:http://linkedlifedata.com/resource/pubmed/id/7422007

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5782
pubmed:dateCreated
1980-12-16
pubmed:abstractText
Erspamer et al. isolated several structurally related non-mammalian peptides, termed tachykinins, with biological activities similar to substance P (refs 2, 3). This similarity is due to a common COOH-terminal region, whereas the specific action of each member of the group depends on its unique NH2-terminal sequence. Based on these properties, parallel bioassays using numerous smooth muscle preparations and physiological parameters allow them to be generally distinguished. However bioassays are time consuming and not highly specific. Thus, we developed a rapid physalaemin-specific radioimmunoassay that led to the initial discovery of a substance in mammalian tissues with an immunoreactivity resembling that of the original amphibian peptide. We now present data on the distribution, localization and partial characterization of physalaemin-like immunoreactivity (PSLI) in tissues of several mammalian species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
287
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
555-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
A neuropeptide in mammalian tissues with physalaemin-like immunoreactivity.
pubmed:publicationType
Journal Article