Linked Life Data

7212227

Source:http://linkedlifedata.com/resource/pubmed/id/7212227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-5-21
pubmed:abstractText
The effect on halothane uptake of changing the nitrous oxide concentration during the first few minutes of a general anaesthetic for Caesarean section was investigated. In 10 mothers anaesthesia was maintained with halothane 0.4%, nitrous oxide 33% and oxygen 66%. In 10 others the sole difference in anaesthetic technique was that the ratio of nitrous oxide to oxygen was reversed for the first 3 minutes only. Serial maternal arterial blood samples showed a significant increase in halothane levels in the group where the nitrous oxide was increased, with p less than 0.02 at 1 and 2 minutes and p less than 0.05 at 3.4 and 5 minutes. After 5 minutes there was no significant difference between the two groups. Cord blood concentrations between the two groups were comparable. The difference in halothane levels is a demonstration of the influence of the concentration effect of nitrous oxide on the uptake of halothane, the second gas effect. The relevance of anaesthetic uptake to obstetric anaesthesia and awareness is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-2409
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Halothane uptake and nitrous oxide concentration. Arterial halothane levels during Caesarean section.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial