Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-2-14
pubmed:abstractText
A comparison was made of the methods of coagglutination (using sensitized staphylococci) and counterimmunoelectrophoresis with regard to (i) sensitivity in detecting capsular polysaccharides from 14 different types of pneumococci, and (ii) sensitivity and specificity in detecting pneumococcal antigen in sputum samples from patients with pneumonia. Counterimmunoelectrophoresis was 20-150 times less sensitive than coagglutination in detecting purified type 7F and 14 polysaccharide preparations, and was as sensitive as or slightly more sensitive than coagglutination in detecting the other 12 polysaccharide types. Of 331 sputum samples examined, 94 were antigen positive, 87 by coagglutination and 76 by counterimmunoelectrophoresis; strong reactions were obtained with 85 and 63 samples, respectively. Moreover, with counterimmunoelectrophoresis 24 samples gave rise to probably non-specific precipitates, while with coagglutination either a strong positive or an unequivocally negative result was obtained in all but six samples. It is concluded that coagglutination is not only simpler and faster than counterimmunoelectrophoresis, but also appears to be more specific and sensitive for the detection of pneumococcal antigen in sputum samples.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0722-2211
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
91-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Diagnosis of pneumococcal pneumonia by coagglutination and counterimmunoelectrophoresis of sputum samples.
pubmed:publicationType
Journal Article