Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-4-7
pubmed:abstractText
Recent studies of the esc+ gene suggest that its product acts principally in the initiation, but not the maintenance, of segmental determination. We have tested this hypothesis by examining when the esc+ gene product is required during embryogenesis, and whether the esc+ gene product is required for the stable determination of imaginal disc cells passaged in in vivo culture. We find that the esc+ gene product is required during a discrete period of embryogenesis. If the gene product is absent or inactive during this period, most segments develop like the eighth abdominal segment. In contrast, absence of active gene product before or after this period has relatively little effect on segmental development. These results support the hypothesis that the esc+ gene product has a discrete early function in the initiation of segmental determination.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Early role of the esc+ gene product in the determination of segments in Drosophila.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't