Linked Life Data

7115145

Source:http://linkedlifedata.com/resource/pubmed/id/7115145

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1982-10-29
pubmed:abstractText
Peripheral blood lymphocytes (PBLs) from patients with multiple sclerosis (MS) were studied to determine the frequency at which they formed rosettes with target cells persistently infected with measles or mumps virus. Results were compared with (1) the rosette-forming capability of lymphocytes from age- and sex-matched normal control subjects and (2) the rosette-forming capability of lymphocytes with uninfected target cells from patients with MS. Comparison of mean measles antibody titers in patients with MS was significantly higher than in control subjects. A similar comparison for mumps antibodies showed a significant differences. There was no significant difference between patients and control subjects in the frequency of lymphocytes that formed rosettes, no matter which target cell was used. When data obtained using target cells infected with measles were analyzed according to sex or clinical classification, no significant difference was observed. Lymphocytes from patients or control subjects formed significantly more rosettes when reacted with virus-infected rather than uninfected target cells. These data suggest that PBL rosette formation with measles- or mumps-infected cells may represent nonspecific adherence rather than specific adherence.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-9942
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
565-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Measles- or mumps virus-infected cells forming rosettes with lymphocytes from patients with multiple sclerosis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't