Linked Life Data

7111279

Source:http://linkedlifedata.com/resource/pubmed/id/7111279

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-10-29
pubmed:abstractText
The bithorax complex is a gene cluster whose function is to regulate still other genes in such a way that each segment of the body commencing with the second thoracic segment and proceeding posteriorly, develops a unique pattern of structures. Numerous cis-regulatory regions have been identified within the complex and are believed to bind to repressor-like substances elaborated by the wild-type alleles of at least two major trans-regulatory genes, Polycomb and extra sex combs. The more proximal is a gene in the complex (with the exception of postbithorax) the more likely it is to be derepressed; the more posterior is a segment in the organism, the greater is the number of BX-C genes that become derepressed in that segment. A gradient in repressor substance(s) and a gradient in affinity of the cis-regulatory regions for repressor can account in a formal sense for the regulation of the BX-C genes themselves.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0361-7742
pubmed:author
pubmed:issnType
Print
pubmed:volume
85 Pt A
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-88
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Control of body segment differentiation in Drosophila by the bithorax gene complex.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.