Linked Life Data

7106521

Source:http://linkedlifedata.com/resource/pubmed/id/7106521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-10-21
pubmed:abstractText
Duodenal fluid was collected from normal volunteers before and after stimulation with pancreozymin-cholecystokinin and secretin. Protein content, proteolytic enzyme activities, and antibody activities against cow's milk proteins, alpha-casein, and beta-lactoglobulin B, were measured in the duodenal fluid. After pancreozymin-cholecystokinin stimulation, immunoglobulin A and immunoglobulin M antibody activities rose to peak levels in 5-10 min. The increase in protein content and proteolytic enzyme activities after pancreozymin-cholecystokinin stimulation paralleled the increase in antibody activity against the two cow's milk proteins. Secretin, in spite of its known dilutional effect on duodenal fluid enzyme concentration, also produced a rise in immunoglobulin M and immunoglobulin A antibody activities. Only a slight increase in immunoglobulin G antibody activity was noted after both pancreozymin-cholecystokinin and secretin. It is suggested that, pancreozymin-cholecystokinin and secretin, in addition to their well-established effects on the release of digestive enzymes, also stimulate release of specific antibodies against food proteins. Release of antibody coincident with food intake may act in preventing the inadvertent absorption of antigenic food proteins.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
916-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Pancreozymin and secretin enhance duodenal fluid antibody levels to cow's milk proteins.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't