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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1981-5-26
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pubmed:abstractText |
A sensitive and reproducible indirect fluorescent antibody test for a North American isolate of Babesia gibsoni was described. In blind tests (coded samples), titer reproducibility was within two 4-fold dilutions and the appropriate positive and negative sera were identified as such. Babesia gibsoni antisera reacted with homologous antigen at one to three 4-fold dilutions greater than with the following heterologous species: B bigemina, B argentina, B equi, Plasmodium falciparum, and P brasilianum. The titer of B canis antiserum to B gibsoni antigen was 1:1,024. low parasitemia (less than 0.01%) of B gibsoni preceded development of minimum significant titer (1:64) by 10 days in a splenectomized dog. Maximum titer was detected 25 days later. In a nonsplenectomized dog, low parasitemia (less than 0.01%) was noted 6 days after injection; it reached 8% at 5 weeks and decreased to and remained below 1% at 7 weeks. A titer of 1:256 occurred at 25 days and increased to 1:65,536 at 18 weeks. Thereafter, it fluctuated to 1:4,096 until the experiment was ended at 24 weeks. organismic antigen retained its reactivity for 5 days at 5 C. This indirect fluorescent antibody test should be useful in the diagnosis of dogs infected with B gibsoni.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2102-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7011131-Animals,
pubmed-meshheading:7011131-Antibodies,
pubmed-meshheading:7011131-Babesia,
pubmed-meshheading:7011131-Babesiosis,
pubmed-meshheading:7011131-Dog Diseases,
pubmed-meshheading:7011131-Dogs,
pubmed-meshheading:7011131-Fluorescent Antibody Technique,
pubmed-meshheading:7011131-North America
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pubmed:year |
1980
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pubmed:articleTitle |
Canine babesiosis: indirect fluorescent antibody test for a North American isolate of Babesia gibsoni.
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pubmed:publicationType |
Journal Article,
Comparative Study
|