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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1980-8-25
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pubmed:abstractText |
P1 infected minicells synthesize approximately 50 phage-encoded polypeptides. Phage expression is temporally controlled, demonstrating phage polypeptides synthesized both early and late after infection. The P1 repressor, gpcl1 (Mr = 33,000), repressor bypass polypeptide, gpreb A (Mr = 27,500) and cistron 10 product, (gp10) (Mr = 64,000), have been identified by infection of minicells with P1 amber mutants. The beta-lactamase gene product (gpbla) carried by the closely related P7 and the chloramphenicol acetyl-transferase gene product (gpcat) carried by P1 Cm (in Tn9) have been demonstrated. Infection of minicells by P1virs or P1c4 mutants results in increased synthesis of gpreb A and a second polypeptide designated gpreb B (Mr = 40,000). The P1vir11 mutation leads to increased synthesis of a small polypeptide (Mr = 3,500) but does not affect the amount of gpc1 synthesized.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0026-8925
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
178
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
149-54
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:6991877-Coliphages,
pubmed-meshheading:6991877-Escherichia coli,
pubmed-meshheading:6991877-Genes, Viral,
pubmed-meshheading:6991877-Lysogeny,
pubmed-meshheading:6991877-Mutation,
pubmed-meshheading:6991877-Repressor Proteins,
pubmed-meshheading:6991877-Transcription Factors,
pubmed-meshheading:6991877-Viral Proteins
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pubmed:year |
1980
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pubmed:articleTitle |
Identification of the repressor and repressor bypass (antirepressor) polypeptides of bacteriophage P1 synthesized in infected minicells.
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pubmed:publicationType |
Journal Article
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