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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1983-3-24
|
| pubmed:abstractText |
The biological activity of potassium dichromate (K2Cr2O7) was assayed in V79/AP4 Chinese hamster cells by measuring two mutational end points, thioguanine (TG) resistance and ouabain (OUA) resistance, and two non-mutational end points, cytotoxicity and sister chromatid exchanges (SCE). By exposing the cells for 1 h to the chemical, all biological end points examined were affected by the treatment in a dose-dependent manner. Moreover the combined use of the two selective systems indicated that chromium induces base-pair substitutions in mammalian cells in culture.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0009-2797
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
42
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
45-51
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6891292-Animals,
pubmed-meshheading:6891292-Cell Line,
pubmed-meshheading:6891292-Cell Survival,
pubmed-meshheading:6891292-Chromates,
pubmed-meshheading:6891292-Cricetinae,
pubmed-meshheading:6891292-Cricetulus,
pubmed-meshheading:6891292-Crossing Over, Genetic,
pubmed-meshheading:6891292-Ouabain,
pubmed-meshheading:6891292-Potassium Dichromate,
pubmed-meshheading:6891292-Sister Chromatid Exchange,
pubmed-meshheading:6891292-Thioguanine
|
| pubmed:year |
1982
|
| pubmed:articleTitle |
Thioguanine resistance, ouabain resistance and sister chromatid exchanges in V79/AP4 Chinese hamster cells treated with potassium dichromate.
|
| pubmed:publicationType |
Journal Article
|