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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1984-3-8
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pubmed:abstractText |
Residual beta cell function based on C-peptide assays was estimated in 39 patients (27 Blacks, 12 Indians) with insulin-dependent diabetes mellitus and 18 controls (9 Blacks, 9 Indians) using glucose as a stimulus. The diabetic patients showed significantly lower maximal C-peptide values (mean 0,53 +/- 0,08 nmol/l) and delayed peak levels (mean 137 minutes after ingestion of glucose) compared with the controls (mean 2,15 +/- 0,31 nmol/l and 54 minutes respectively). Just over 20% of the patients had no residual beta cell function, this conclusion being made on the basis of undetectable basal C-peptide levels which failed to rise after glucose stimulation. A significant correlation was seen between glycosylated haemoglobin levels and maximal C-peptide levels (r = 0,45, P less than 0,01). C-peptide levels tended to be lower in Black than in Indian patients, but the difference was not significant.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0256-9574
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
4
|
pubmed:volume |
65
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
155-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6695271-Adolescent,
pubmed-meshheading:6695271-Adult,
pubmed-meshheading:6695271-Blood Glucose,
pubmed-meshheading:6695271-C-Peptide,
pubmed-meshheading:6695271-Child,
pubmed-meshheading:6695271-Diabetes Mellitus, Type 1,
pubmed-meshheading:6695271-Female,
pubmed-meshheading:6695271-Glucose,
pubmed-meshheading:6695271-Glucose Tolerance Test,
pubmed-meshheading:6695271-Hemoglobin A, Glycosylated,
pubmed-meshheading:6695271-Humans,
pubmed-meshheading:6695271-Male,
pubmed-meshheading:6695271-Time Factors
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pubmed:year |
1984
|
pubmed:articleTitle |
C-peptide response to a glucose load in young blacks and Indians with insulin-dependent diabetes mellitus.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|