Source:http://linkedlifedata.com/resource/umls/id/C0006558
MSH: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.,NCI: A substance made by the pancreas. C-peptide and insulin are both part of a larger molecule that gets split apart before being released into the blood. Abnormal blood levels of C-peptide may occur in certain diseases, such as diabetes or cancer.,NCI: C peptide (31 aa, ~3 kDa) is encoded by the human INS gene. This protein is involved in both signal transduction and the modulation of blood flow.