Linked Life Data

6693434

Source:http://linkedlifedata.com/resource/pubmed/id/6693434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-3-16
pubmed:abstractText
When cultured Drosophila line S3 cells are incubated in the presence of the steroid hormone, ecdysterone, they flatten, elongate, and become motile. We show here that accompanying this morphological transformation there is a 5-fold increase in the rate of actin synthesis and a 2-fold increase in actin content. These increases, in turn, are primarily based on a 9-fold increase in the level of mRNA transcribed from the cytoplasmic actin A3 gene. We also find that during hormone treatment the cells go into proliferative arrest, accumulating in the G2 phase of the cell cycle. During this period the level of histone mRNA in the cells decreases significantly.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-9258
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
259
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1738-43
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.