Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-2-21
pubmed:abstractText
Sister chromatid exchange (SCE) induction by two radiosensitizing platinum compounds (cis-dichloro-bis isopropylamine trans dihydroxy platinum IV (CHIP) and cis-platinum metronidazole2 Cl2 (FLAP] was studied in CHO cells in vitro. Both drugs induced SCE in a dose dependent manner. CHIP was a much more potent inducer of SCE than FLAP and produced almost 4 times as many SCE as FLAP at equimolar concentrations and twice as many at equitoxic dosage. Induction of SCE by a component of the FLAP molecule--metronidazole--was also examined. It did not cause any increase of SCE frequency over the control level when applied at 10 times the highest concentration of FLAP which was used.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-1207711, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-1240592, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-392602, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-4138930, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-440327, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-528286, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-52847, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6156589, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6182579, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6849795, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6890846, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6984033, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-6987501, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-714079, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-7378711, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-74232, http://linkedlifedata.com/resource/pubmed/commentcorrection/6652019-954143
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-0920
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
803-7
pubmed:dateRevised
2011-9-13
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Sister chromatid exchanges induced by two radiosensitizing platinum compounds (cis-dichloro-bis isopropylamine trans dihydroxy platinum IV (CHIP) and cis platinum metronidazole2Cl2(FLAP)) in CHO cells in vitro.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't