Linked Life Data

6427080

Source:http://linkedlifedata.com/resource/pubmed/id/6427080

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-6-22
pubmed:abstractText
The liver, lung and mesenteric adipose tissue of three patients with 'yusho', polychlorinated biphenyl (PCB) poisoning, and two control persons were analysed for methylthio and methylsulphone metabolites of PCBs by gas chromatography with electron capture detection, gas chromatography-mass spectrometry and mass fragmentography. The tissues were shown to contain two congeners of methylthio PCBs with four chlorine atoms, and 16 congeners of methylsulphone PCBs with three, four, five or six chlorine atoms. The concentrations of methylthio PCBs in the liver, lung and adipose tissue of the yusho patients were 0.1-0.5, 0.2-1.4 and 0.5-1.0 micrograms/kg, respectively, and those of methylsulphone PCBs were 0.3-0.7, 1.0-2.5 and 0.7-1.0 micrograms/kg, respectively. The concentration ratios of methylthio and methylsulphone PCBs to unchanged PCBs were 1-2% in the liver, 4-8% in the lung and 0.1-0.2% in the adipose tissue for yusho patients, indicating that these metabolites accumulate slightly more in the lung and liver than in the adipose tissue, relative to PCBs. The tissue levels of the PCB metabolites in control persons were about one tenth of those in yusho patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0278-6915
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Determination of methylthio and methylsulphone polychlorinated biphenyls in tissues of patients with 'yusho'.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't