Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1985-6-6
pubmed:abstractText
Plasma vasoactive intestinal polypeptide (VIP) increased significantly in the portal vein, the superior caval vein, the internal jugular vein, and the aorta during an intravenous infusion of E. coli endotoxin in six anesthetized pigs, which all developed a deep shock, with fall in aortic blood pressure and urinary output. Plasma VIP peaked simultaneously with the most pronounced shock symptoms, and the level in the portal vein was significantly higher than in blood from the other sampling sites. In contrast, no significant change in plasma secretin was noted. It is suggested that the gastrointestinal tract is the main source of the high plasma VIP levels seen during endotoxinemia and that VIP may play a significant role in endotoxin shock.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0036-5521
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1048-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Portal and systemic plasma VIP and secretin during intravenous infusion of Escherichia coli endotoxin in pigs.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't