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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1984-7-20
|
| pubmed:abstractText |
Gastric cancer specimens obtained from 162 patients who had undergone radical surgery with the routine postoperative administration of both mitomycin C and 5-fluorouracil were stained for carcinoembryonic antigen (CEA) by the unlabeled antibody enzyme technique. The CEA (-/+) group (92 cases) consisting of the negative and weakly positive staining cases had a significantly better survival rate over a period of 5 years than the CEA (++) group (70 cases) which comprised only strongly positive cases. The CEA (-/+) group with differentiated adenocarcinoma had the best prognosis and the 5-year survival rate was significantly higher than those of the other three groups. Among stage II and III carcinomas, the postoperative survival rate was significantly better in the CEA (-/+) group than in the CEA (++) group. Among the patients with lymph node metastasis, the postoperative survival rate was low, especially in the CEA (++) group. The present data suggest that staining for CEA in tissue sections of stomach carcinoma may be helpful in differentiating among tumors that appear similar by conventional histological methods, thus providing a new means for obtaining more precise prognostic information.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0016-450X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
75
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
230-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1984
|
| pubmed:articleTitle |
Correlation between carcinoembryonic antigen in gastric cancer tissue and survival of patients with gastric cancer.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|