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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0006558,
umls-concept:C0021641,
umls-concept:C0040374,
umls-concept:C0087111,
umls-concept:C0205112,
umls-concept:C0348016,
umls-concept:C0439590,
umls-concept:C0441889,
umls-concept:C0871261,
umls-concept:C1511790,
umls-concept:C1546940,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
1983-8-11
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pubmed:abstractText |
Fifty nine insulin dependant diabetics were hospitalised for a trial withdrawal of insulin: 17 patients rapidly showed signs of lack of insulin, 18 did not develop cetoacidosis but could not be stabilised on diet and oral hypoglycemic agents, 24 were stabilised without insulin. A statistical study (multifactorial analysis of correlations, plotting of ROC graphs) validated the classification of these diabetics into 3 groups. It also showed that in patients with hypoglycemia, the values of C-protein, and after intravenous injection of tolbutamide, were good predictive factors for insulin-dependance: all patients with basal C-protein less than 1,9 ng/ml could not be stabilised without insulin; when the basal C-protein greater than or equal to 1,9 ng/ml and the amplitude of response at the 5th min was greater than or equal to 0,4 ng/ml, the diabetes could be stabilised by diet and oral hypoglycemic agents in 90 p. 100 of cases. This institutes an easy, reliable and economic method of detecting abusive insulin therapy.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0248-8663
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6346452-Adolescent,
pubmed-meshheading:6346452-Adult,
pubmed-meshheading:6346452-Aged,
pubmed-meshheading:6346452-C-Peptide,
pubmed-meshheading:6346452-Diabetes Mellitus,
pubmed-meshheading:6346452-Female,
pubmed-meshheading:6346452-Humans,
pubmed-meshheading:6346452-Injections, Intravenous,
pubmed-meshheading:6346452-Insulin,
pubmed-meshheading:6346452-Male,
pubmed-meshheading:6346452-Middle Aged,
pubmed-meshheading:6346452-Peptides,
pubmed-meshheading:6346452-Tolbutamide
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pubmed:year |
1983
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pubmed:articleTitle |
[Basal C peptide levels in response to intravenous tolbutamide in the detection of incorrect insulin therapy (or prolonged misuse)].
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pubmed:publicationType |
Journal Article,
English Abstract
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