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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-5-5
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pubmed:abstractText |
Blood specimens were collected over various periods of time from 30 abattoir workers with a clinical diagnosis of Q fever. All specimens were tested for complement-fixing antibodies and for specific immunoglobulin M (IgM) globulins to phase 1 and 2 Coxiella burnetii organisms by an immunofluorescence technique. All 22 patients with increasing levels of complement-fixing antibodies were shown to have generated specific IgM globulins, as did 4 patients with high convalescent titers but from whom "acute" specimens were not collected. Four individuals who did not show increasing levels of complement-fixing antibodies did not produce measurable levels of specific IgM. All patients with Q fever gave positive specific IgM results by 2 weeks after the onset of symptoms. IgM to phase 1 antigen persisted for 27 weeks in one patient, but IgM to phase 2 antigen was not detectable beyond 17 weeks. The estimation of Q fever-specific IgM has proved useful in confirming infection when only a "convalescent" blood specimen is available.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6339396-14946397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6339396-35962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6339396-5431751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6339396-7432817
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0019-9567
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
977-81
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6339396-Abattoirs,
pubmed-meshheading:6339396-Antibodies, Bacterial,
pubmed-meshheading:6339396-Complement Fixation Tests,
pubmed-meshheading:6339396-Coxiella,
pubmed-meshheading:6339396-Fluorescent Antibody Technique,
pubmed-meshheading:6339396-Humans,
pubmed-meshheading:6339396-Immunoglobulin M,
pubmed-meshheading:6339396-Q Fever,
pubmed-meshheading:6339396-Serologic Tests,
pubmed-meshheading:6339396-Time Factors
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pubmed:year |
1983
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pubmed:articleTitle |
Immunoglobulin responses to Coxiella burnetii (Q fever): single-serum diagnosis of acute infection, using an immunofluorescence technique.
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pubmed:publicationType |
Journal Article
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