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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1984-2-15
|
| pubmed:abstractText |
A kinetic model of the sodium channel gating system consisting of four subunits with three states--closed (X), open (Y) and inactivated (Z)--is proposed. For the channel to conduct, all the four subunits must be in the open state. The transitions between states X and Y are independent, while those between states X and Z are coupled, so that for the particle considered transition of one of two neighbouring particles into state Z increases the activation energy of the step by kT. The model fits rather well to the experimental data.
|
| pubmed:language |
rus
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0041-3771
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1325-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6318412-Animals,
pubmed-meshheading:6318412-Cell Membrane,
pubmed-meshheading:6318412-Ion Channels,
pubmed-meshheading:6318412-Kinetics,
pubmed-meshheading:6318412-Mathematics,
pubmed-meshheading:6318412-Models, Biological,
pubmed-meshheading:6318412-Rana ridibunda,
pubmed-meshheading:6318412-Ranvier's Nodes,
pubmed-meshheading:6318412-Sodium
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
[Kinetic model of the gating system of the sodium channel in a Ranvier node membrane].
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|