|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0010453,
umls-concept:C0012550,
umls-concept:C0026882,
umls-concept:C0031437,
umls-concept:C0033414,
umls-concept:C0039654,
umls-concept:C0086418,
umls-concept:C0441472,
umls-concept:C0683598,
umls-concept:C1706701
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|
pubmed:issue |
24
|
|
pubmed:dateCreated |
1983-6-10
|
|
pubmed:abstractText |
Stable spontaneous mutants resistant to the protein synthesis inhibitor diphtheria toxin (DT) have been selected in human cell line eue at a very low frequency (8 x 10(-6)). We have studied in this system the effect of the promoting agent phorbol-12-myristate-13-acetate (TPA) on mutagenesis induced by benzo(a)pyrene (BP). TPA did not increase the mutation frequencies induced by BP, but it showed a trend to make shorter the expression time.
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|
pubmed:language |
ita
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0037-8771
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
30
|
|
pubmed:volume |
58
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1679-84
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:6301518-Benzo(a)pyrene,
pubmed-meshheading:6301518-Benzopyrenes,
pubmed-meshheading:6301518-Cell Line,
pubmed-meshheading:6301518-Cells, Cultured,
pubmed-meshheading:6301518-Diphtheria Toxin,
pubmed-meshheading:6301518-Drug Resistance,
pubmed-meshheading:6301518-Epithelium,
pubmed-meshheading:6301518-Female,
pubmed-meshheading:6301518-Humans,
pubmed-meshheading:6301518-Mutation,
pubmed-meshheading:6301518-Phenotype,
pubmed-meshheading:6301518-Phorbols,
pubmed-meshheading:6301518-Pregnancy,
pubmed-meshheading:6301518-Tetradecanoylphorbol Acetate
|
|
pubmed:year |
1982
|
|
pubmed:articleTitle |
[Promoting action of tetradecanoylphorbol acetate on the phenotypic expression of the mutation for the acquisition of resistance to diphtheria toxin in cultured human cells].
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|
pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
|
