Source:http://linkedlifedata.com/resource/umls/id/C0012550
MSH: An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.,CSP: ADP ribosylating exotoxin produced by Corynebacterium diphtheriae that causes the signs and symptoms of diphtheria; it can be broken into two unequal domains, the smaller, catalytic A domain is the lethal moiety and contains mono ADP ribose transferase which transfers ADP ribose to peptide elongation factor 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.