Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-11-23
pubmed:abstractText
The Xenopus laevis oocyte provides a convenient system for studying cell cycle-induced changes in RNA metabolism. Initially arrested at first meiotic prophase, it can be induced in vitro to undergo maturation by incubation in the presence of progesterone, progressing to second meiotic metaphase over the course of several hours. The dissolution of the nuclear membrane before the onset of first meiotic metaphase (also known as germinal vesicle breakdown, or GVBD) provides a convenient indication of the overall rate of maturation. It is reported that all ordinarily unstable classes of nuclear RNA show substantial increases in stability following GVBD. However, some radioactivity in rRNA precursors disappears following GVBD and this is quantitatively accounted for by the appearance of label in mature rRNA. These results suggest continued processing of rRNA precursors after GVBD.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
427-36
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
RNA stabilization and continued RNA processing following nuclear dissolution in maturing Xenopus laevis oocytes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.