Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1983-9-20
|
pubmed:abstractText |
The cytostatic effect of murine interferon (IFN) on several BALB/c-derived B- and T-cell tumor cells was examined. After incubation for 1 h in vitro with 1000 U of IFN, followed by intraperitoneal inoculation, tumor formation was not decreased in the case of B cell tumors or Lyt-1+2- or Lyt-1+2+3+ T cells tumors. Under the same conditions, the onset of tumor formation for Lyt-2+3+ T-cell tumors was delayed and the final incidence decreased. When the effect of IFN on cell multiplication in vitro was examined, Lyt-2+3+ T-tumor cells were found to be more sensitive to the cytostatic effect of IFN than Lyt-1+2+3+ T-tumor cells. This shows that the sensitivity of lymphocyte-derived tumor cells to the cytostatic effect of IFN is influenced by the type of differentiation of the cells.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0197-8357
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
3
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
253-60
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6192189-Animals,
pubmed-meshheading:6192189-B-Lymphocytes,
pubmed-meshheading:6192189-Cell Differentiation,
pubmed-meshheading:6192189-Interferons,
pubmed-meshheading:6192189-Mice,
pubmed-meshheading:6192189-Neoplasm Transplantation,
pubmed-meshheading:6192189-Neoplasms, Experimental,
pubmed-meshheading:6192189-T-Lymphocytes
|
pubmed:year |
1983
|
pubmed:articleTitle |
Differential cytostatic effect of interferon on murine BALB/c B- and T-cell tumors.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|