Linked Life Data

6144433

Source:http://linkedlifedata.com/resource/pubmed/id/6144433

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-7-10
pubmed:abstractText
[3H]serotonin binds to two classes of sites in a crude membrane preparation of Drosophila melanogaster heads, with apparent Kd values of 1.4 and 130 nM, and a concentration of 0.2 and 1.5 pmol/mg protein, respectively. High salt concentration and a guanyl nucleotide decrease the number of the high-affinity binding sites. Low concentrations of ergot alkaloids, various tryptamine derivatives, neuroleptic drugs, but not of phentholamine , propranolol and dopamine, displace [3H]serotonin from its high affinity sites. The relevance of the [3H]serotonin-binding sites to serotonin receptors in Drosophila is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0742-8413
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-9
pubmed:dateRevised
2007-7-23
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[3H]serotonin binds to two classes of sites in Drosophila head homogenate.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, U.S. Gov't, Non-P.H.S.