Linked Life Data

6104083

Source:http://linkedlifedata.com/resource/pubmed/id/6104083

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8181
pubmed:dateCreated
1980-8-25
pubmed:abstractText
279 patients were treated with 100 mg trimethoprim or 100 mg trimethoprim combined with 500 mg sulphamethoxazole (co-trimoxazole) twice daily for 5 days in a prospective randomised double-blind trial. In chest infections in patients in general practice and in an acute geriatric assessment unit, the efficacy of each regimen was similar, but there were more side-effects with co-trimoxazole than with trimethoprim alone. In urinary-tract infections the two regimens also produced similar cure rates. Treatment with trimethoprim rarely selected resistant pathogens in the sputum or resistant Enterobacteriacae in the intestine, although the incidence of resistant coagulase-negative staphylococci on the skin increased with both regimens. Most chest and urinary infections hitherto treated with co-trimoxazole should be treated with trimethoprim alone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1270-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Comparison of trimethoprim alone with trimethoprim sulphamethoxazole in the treatment of respiratory and urinary infections with particular reference to selection of trimethoprim resistance.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial