Linked Life Data

6091916

Source:http://linkedlifedata.com/resource/pubmed/id/6091916

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-12-12
pubmed:abstractText
The species and tissue specificities of gap junction polypeptides were investigated with antibodies raised against the 27,000 dalton rat liver gap junction protein. Cross-reacting 27,000 dalton polypeptides were detected in liver from mammalian, fish, and avian species by immunoreplica analyses and were localized to punctate regions of the plasma membrane by indirect immunofluorescence. They were also found in homogenates of other rat tissues, including pancreas, heart, brain, kidney, stomach, and adrenal gland, but not in lens fiber material. Localization of antibody binding in pancreas was similar to that of liver, while in heart ventricle the immunofluorescence pattern was consistent with binding to the intercalated disc. These findings indicate that homologous gap junction polypeptides may be widely distributed among vertebrate tissues.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
A protein homologous to the 27,000 dalton liver gap junction protein is present in a wide variety of species and tissues.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't